Johannesburg - Six people, two of them children, were killed in an accident on the N11 near the Dundee off-ramp on Sunday evening, paramedics said.
Paramedics arrived to find that six people, including a 4-year-old and an 8-year-old, died in the crash, ER24 spokesperson Werner Vermaak said.
It was believed that all those killed had been travelling in the same car.
Four people, from the second vehicle, were taken to hospital with serious injuries.
The cause of the accident was unclear.