Yangon - Police said on Saturday that 19 people were killed and 21 injured after their bus toppled into a ravine in eastern Myanmar.
The bus was carrying around 40 passengers from central Bago province when it plunged off a highway near Myawaddy, a town on the Thai border.
Kyi Lin, the chief of police in Karen state said: "(The bus) fell down into a narrow and deep gorge," he said, adding that police believe the driver lost control of the bus because of a brake failure".
Police and local aid groups have brought the injured to nearby hospitals for urgent care and are making funeral arrangements for the dead, he added.
A hospital in Mae Sot, the Thai town across the border, took in seven patients from the crash who were in "critical condition,"said a medical worker.
Road accidents are common in impoverished Myanmar, whose transport network is in poor condition after decades of under-investment by the junta that ruled the country for almost half a century until early 2011.