Flight MH192, with 159 passengers and seven crew, had been heading from Kuala Lumpur to Bangalore, the airline said.
The problem was with the right-hand landing gear of the Boeing 737-800 aircraft, it said.
"Malaysia Airlines is currently working with the Airport Fire Rescue Services [AFRS] in anticipation of the landing," the airline said in a statement.
Last month a Malaysian Airlines flight disappeared on a flight from Kuala Lumpur to Beijing in unexplained circumstances, and the search for its presumed wreckage is still continuing in the Indian Ocean.