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"From my point of view, hopefully things will be resolved and we can get a green light to go ahead and play against South Africa," Gayle said on Friday in Johannesburg.
The West Indians pulled out of their recent tour of India midway through the series with an ODI, T20 International and three Tests remaining.
"It's just unfortunate where things are at the moment, but these things tend to happen in industries," he said.
"Before I left the Caribbean, there was a meeting held between Dwayne Bravo and the board. I don't know what the outcome was, and we'd love to see the cricket go on because that's what we're here for.
"It will make the people feel happy to see some good cricket."
The West Indies are scheduled to play three Tests, three T20 Internationals and five ODIs in South Africa, kicking off with the first Test at Centurion on December 17.
While he was reluctant to say West Indian cricket was in turmoil, Gayle did admit the current environment was far from ideal.
"I wouldn't say this is a low point for West Indies cricket, we've had other issues in the past and things were resolved.
"But it has been better, there's no doubt about it."
Gayle was hopeful the issues between players and the board would be sorted out soon.
"We're just trying to get things resolved as quickly as possible and there are no hard feelings."
The T20 specialist met up with his Highveld Lions teammates ahead of their opening T20 franchise match against the Dolphins -- part of a triple-header at the Wanderers on Sunday.
