A mother and her child died in a crash involving three vehicles on the N2 highway near Zinkwazi, on the north coast of KwaZulu-Natal on Friday, paramedics said.
"Paramedics worked together to treat four surviving victims from the crash," KZN emergency medical services spokesperson Robert McKenzie said.
He said several survivors were airlifted to hospital for continued medical care.
The cause of the crash was not immediately known, but police were investigating, McKenzie added.
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